GOUT, first flare up in two years


I am a long time gout sufferer and it has been under control with minimal medication and diet. I just started Soylent for one week and have had a rather nasty flare up and had to go on Colchicine for treatment. I am wondering if anyone else has had this issue and if we know what the level of purines is contained in Soylent?




I haven’t seen mention of purine levels in Soylent. I’m bumping this thread to get more feedback on it.

The protein source, rice protein, should not have significant purine in it - but oat flour is a major component, and oats are relatively high in purines.

Also, I’ve seen mention that dairy protein tends to be protective against gout; if you’re not consuming any more dairy, you may be more sensitive to the purines in the oats. (This is strictly speculation.)


I had a similar experience with my first use of Soylent (V1.2).

I received my first order last week and tried 1/3 pouch. Within 8 hours I had a significant flare up. It could certainly be unrelated, but was interested to see others experience the same. I have not tried a second round but will again next week when things settle down.


When I saw the first post in this thread I thought, okay, one person, maybe coincidence, but now that there is another it worries me.

I looked it up and it does seem that oats are high in purines but all the different cases and scenarios confuse me. And the Soylent ingredient says oat flour rather than oats. And of course there are a bunch of other ingredients on Soylent too so does Soylent as a whole come down as high in purines? I don’t know. I wish I did.

In first reading about this I saw Rob Rhinehart say something that really struck a chord with me. He said that in the past it was, healthy and cheap and fast, pick two. And that the point of Soylent was to hit all three. And I love that idea. But the problem may be that although most people are basically the same, there is enough variation that no matter what you put in there, there will be a minority of folks who it doesn’t agree with.

Gout isn’t extremely common but it’s my understanding that it’s far from rare too so if Soylent is bad for gout then that will eliminate some. I love the idea of Soylent but I love even more being able to walk without terrible pain. I’ve not had much Soylent so far but I do have it on a “one week per month re-order” basis and I’ve been meaning to ramp up but now I’m a bit worried about doing so.

It would be nice to be able to get good info but the world of nutrition seems to be so nebulous with so many different opinions. And in addition to genuinely different opinions there also seem to be lots of biases out there, and especially against Soylent because the idea creeps out so many. And as far the Soylent folks themselves go, I’m grateful for them coming up with Soylent but I’d be reticent to just automatically believe them if they say, trust us, it’s low in purines. It sure would be nice if there was an independent and non-biased entity to check such things.

ETA: Also, while you can research which foods are high in purines I get the impression that some high purine foods may be more prone to causing gout than others (we don’t really know) and/or that some people may be more susceptible to having their gout kick in from eating Food X while other people are fine with Food X but Food Y is gout-causing for them (we don’t really know). It seems we don’t really know a lot. Frustrating.


I have Gout and am taking Allopurinol to minimize its effects. In my recent tryout of Soylent 1.1 for a week, my Gout was not affected. I just received a two-week supply of 1.2 and will report any changes. I doubt there is any relationship between Gout and Soylent, but ya never know.


Are you saying you consumed nothing but Soylent 1.1 for a week and had no issues? If so that’s a pretty strong indication that it won’t necessarily cause issues although of course individual variability can come into play for different people.

I hope people with a past history of gout that are trying Soylent keep us updated on their experience.


Yes, that’s what I’m saying. My gout has never been very severe, though, but I am taking daily medicine for it. As was commented, gout is mysterious.


The main ingredients in Soylent (which contribute to the macros) are the fats (canola and algal oil), the protein (rice protein), maltodextrin (from corn starch), and oat flour.

Oat flour is just ground oats, and will be high in purines, just like oats. If you suffer from gout and are sensitive to purines, it’s definitely a concern - a major ingredient known to be high in purines in a food product you eat all day is a recipe for trouble.

The others:
rice / rice protein - low in purines
maltodextrin / starch / corn - low in purines
canola oil - seems low in purines, but I’m not happy with my sources
algal oil - I really don’t know, and I’m not easily finding the answer from reputable sources.

Anybody find a hit on algal oil, one way or the other? Refined fish oil is low in purines, even though fish flesh is high in purines, but I’m not clear on algal-sourced oil.

For conditions like gout, I think the reason it seems very variable is because as individuals, we’re very bad at taking everything into account. One person says sardines are killer, another says they’re not bothered… but maybe the person that’s not bothered only has a little bit with some cracker, while the person who has problems with sardines likes to eat a whole tin of them while chatting with friends over a couple of beers… but that’s a lot more sardines, and the beer is a problem, too!

The other thing to remember is that most foods contain purines. It’s just a question of the level in each. It’s generally a mistake to focus just on one thing you ate if you have an attack - everything you ate was contributing to the overall load. Gout isn’t a response to a particular food, it’s a response to the overall purine level (and to the other things that contribute to uric acid, like fructose.) If someone eats a lot of moderate-purine foods and tops it off with some liver pate, maybe they have a problem. But if someone else eats a lot of low-purine foods and tops off with the same liver pate, maybe they’re OK.


I just read a scientific article on gout that specified: “especially high purine levels found in organ meat, seafood, and alcohol (yeast)”, which makes me think that the recent change in making Soylent vegetarian would be good for gout sufferers.


That makes sense at a glance, but the fish oil actually has low levels of purines (in spite of the fish itself having high levels of purines), and there’s no organ meat or alcohol in Soylent. In fact, switching to algal oil could actually result in higher levels of purine if, for example, some of the purine in fish came from the algae which the fish’s body absorbed, though this seems unlikely.

MentalNomad pretty much makes the best case for this: Oats oats oats oats oats.


Sorry to resurrect an old thread, but I’m a gout sufferer as well. I was on Allopurinol (300mg/day) but had stopped taking it a few weeks before starting Soylent just to see what happened. For the first couple weeks on it I was consuming it as approx 80% of my weekly nutrition, but kinda tailed off to 20-60% after that as the shiny wore off. Forgot to re-order for a while after going through my original backer order, so I’m waiting on a subscription shipment now.

I didn’t experience any problems, but YMMV depending on how bad your condition is and what drugs you’re taking. I really think that most of my flairs were triggered by dehydration, which increases the concentration of uric acid in your system. I can always feel the flair coming on as an ache in the joint, and if I just drink the hell out of water I’ve been able to fend off every flair after stopping the drugs. Note that I am NOT recommending that anyone not take their prescriptions, I did so at my own risk. Allopurinol should in theory protect you if your’e on it and consume Soylent, as it basically interferes with the body’s processing of purines, thus limiting the uric acid byproduct of said processing.

Also, because of what gout actually is, crystallization of uric acid in the soft tissue of the joints when the concentrations get too high, it is unlikely that changing your diet for just a few days is going to have an immediate effect unless you were already right on the edge of a flairup already. If your rheumatologist is regularly monitoring your uric acid levels, this shouldn’t be the case unless it has been mentioned to you.

All of that said, gout sucks. Bad. I have literally felt your pain.


It’s nice to get some gout education, thanks all. I’m still not having any flaireups and am liking Soylent more and more; I started with a one-week shipment, then a two-week shipment, and am going to a full monthly subscription in a few weeks. I’ve never had what I would call a really bad gout attack, and I hope my daily Allopurinol keeps it that way! I had never heard of a rheumatologist till the message above.


FWIW, my gout seems less acute as I wind up a month on Soylent and look forward to continuing my subscription.


You know just throwing this out there because a lot of gout people might click on it. My dad thought he had gout for a couple decades, every few months huge flareups lot of medication unable to walk etc. It even seemed to correspond to certain foods that gout does.

I mean it was bad. he’d seen several specialists and doctors.

Finally the doctor had a NP or something I think… .and she was like maybe it’s psuedo gout. He’d never heard of it and none of the other doctors had ever mentioned anything about it. She took him off one of his medications (I think it was a diuretic or something maybe blood pressure med?) and he hasn’t had a flare up since (several years ago).

Just wanted to throw that out there since, you know, it could help someone maybe.


I am also a gout patient. After 9 days of Soylent 1.4 twice daily, I have undeniably had the first gout flare I’ve experienced while on my maintenance meds. It would be helpful if the FAQ included some information on the purine levels of the ingredients.


After about four months of a complete Soylent diet, my gout is far less active than it has been for years before I started Soylent.


I just started on Soylent 1.5, 3 weeks ago. Only a third of a bag in the morning. I’ve never had gout before in my life but I now have it. I am a 54 year-old male. I have gone back in memory over the last 3 weeks as to what else I have had to eat and drink and I have actually not had any alcohol except for maybe a beer or two. I have also not had much red meat either or some of the other things that can contribute to gout. As I normally have cereal or eggs in the morning, I haven’t had any milk in the past 3 weeks. Low fat milk is supposed to help with cleaning our uric acid. Coffee too is supposed to help and I don;t drink much coffee.

I wonder if the high purines in oat flour were a contributing factor and also wonder if the high number of other vitamins and minerals in the Soylent were taxing on my liver and kidneys and that this caused the liver and kidneys to not function well enough to remove the uric acid in the blood stream?

Anyway, I had a blood test today and I’m going off of Soylent for now so we’ll see in a couple of weeks what the result is. Hopefully, they’ll give me another follow up blood test to see if it makes a difference. I don’t know if I should go back on Soylent after this is over. I’m kind of afraid to now.


My impression is that gout doesn’t happen because of something you started doing three weeks ago. It is a long term condition.


I’m about an 8 pouch a month person. I had a few pouches of 1.4 left and instead of ordering my usual 7 per month when 1.5 came out, I ordered 28 and then paused the subscription, with the idea that 1.4 was okay (not crazy about the aftertaste, but no biggie) and that the reviews were that 1.5 weren’t too different than 1.4 and that I could save a few bucks buying 28 at once.

Two weekends ago I had my first pouch of 1.5. I usually have one pouch during the week and one pouch on weekends. When I had my first pouch of 1.5 two weekends ago, lo and behold I have my first gout episode in some months. At this point when it first starts coming on I know to pound some anti-flammatories and watch the diet and hope it goes away, which it usually does. But I’ve had a couple episodes in the past that made me realize how bad it can be.

Okay, so two weekends ago I had my first pouch of 1.5 then had a gout flare and got cautious and hit the anti-flammatories and then during the week I didn’t have any Soylent at all and the gout went away. Then this last weekend I tried another pouch of 1.5. I had about half a pouch on Saturday and on Sunday the gout started to come back a bit and I said “Darn, that gout isn’t going away” and then it dawned on me…it started coming back when I had more 1.5. So that kinda worries me. It could be coincidence, or maybe not, I don’t know.

I wish there was a way to know if 1.5 has more whatever…purines I think it is…than does 1.4. But anyway, I’m a bit wary now and I’ll be much more watchful the next time I have 1.5. (I have some 1.4 at work that I have during the week sometime but it hasn’t seemed to give me any problems.)

So anyway, just thought I’d throw that out there. I’d be interested in hearing the experiences of others, either positive or negative. There certainly is some way to make a fast, easy, cheap food that doesn’t aggravate gout but that doesn’t necessarily mean they’ve figured it out yet.


Are you taking allopurinol? I’m not suggesting you do, just asking. My gout has become almost invisible since I started Soylent, but I’ve been taking allopurinol for about four years for gout.