Macronutrient Ratio


I didn’t realize that the doctor that came up with the major shift toward fat which started in version 1.4 is the same person that came up with the original macronutrient ratio. Note: I find the product much easier to digest since the newer versions with higher fat. But I nonetheless find the below interesting.

Soylent regarding version 1.0:

As advised by our nutritional advisor, F. Xavier Pi-Sunyer, M.D., MPH, Soylent has a Carbohydrate/Fat/Protein ratio of 50/30/20. Pi-Sunyer is professor of medicine at Columbia University College of Physicians and Surgeons in New York City. At St. Luke’s-Roosevelt Hospital Center he serves as chief of endocrinology, diabetes, and nutrition, and is director of the New York Obesity Research Center. Dr. Pi-Sunyer is also a senior attending physician at St. Luke’s-Roosevelt Hospital and New York-Presbyterian Hospital. This and general agreement within the field gives us confidence that this is a good macronutrient ratio for the general population.

Regarding version 1.4:

Version 1.4, introduced in February 2015, used a carbohydrate/fat/protein calorie ratio of 43/40/17, based on the advice of F. Xavier Pi-Sunyer, a professor of medicine at Columbia University.[52]


“In 1995, when he was appointed to chair the NIH panel that re-classified many Americans as “overweight,” he was also the Executive Director of the Weight Watchers Foundation. In 1997, he joined the Board of Directors of the Weight Watchers Foundation - one year prior to the publication of the NIH report he chaired that lowered the weights at which Americans were considered overweight.
Critics point to his further conflict of interest, noting that ‘he is also on the advisory board or is a paid consultant to several diet and pharmaceutical companies, including Wyeth-Ayerst labs (makers of the fen-phen diet drug that ended up causing heart valve damage), Knoll, Eli-Lilly Pharmaceuticals, Genentech, Hoffman-La Roche, Neurogen, and Weight Watchers International. Pi-Sunyer has been the highly paid principal investigator on recent clinical trials of the drug Rimonabant made by Sanofi-Aventis. Indeed, Pi-Sunyer has been named in a lawsuit against the drug company Wyeth-Ayerst because he agreed to have his name attributed to scientific articles about the cost of obesity that were actually written by Excerpta Medica, a medical consulting firm, and paid for by Wyeth-Ayerst.’”

If you lie, he’ll swear to it - for the right price.