Wow, that’s incredibly thorough. Thanks! This will help direct the search for hard numbers a great deal.
The zinc-copper interaction is mutually deleterious. If the ratio is higher than 15:1 in favor of zinc, then copper will be inhibited. If it’s significantly less than 8:1, then copper will inhibit zinc. The only reliable source I can find states the optimal ratio is 10:1, but I’ve seen anecdotal claims that that is incorrect and 8:1 is actually optimal.
The involvement of Iron and Manganese makes things a bit messy too… Iron will deplete zinc past a ratio of 2:1 in favor of Iron. I haven’t found numbers on the Iron-copper relationship or the Manganese-anything relationship yet.
…the solution of taking micros at different times is valid.
Absolutely. I hope I didn’t give the impression I was dismissing @Chris_Tanti’s point on that. What I want to know is that if we do take everything at once, what ratios would make the staggering unnecessary in general for any healthy person. Or is that even possible, considering everyone has different specific needs.
An alternative to this approach would be to define a set of 3 nutrient sub-DRIs. A breakfast-lunch-dinner profile that gives you what you need in waves that have minimal negative interactions and maximum positive interactions. But that would require 3 different recipes, which I’m personally not as motivated to push for.
This could be a reason why whole foods are good for you because they physically separate the nutrients, so deletorious reactions simply don’t happen.
Are there vitamin/mineral combinations that actually react with each other, even outside the GI tract? As I understand the problem, at least for what I’ve seen so far, it’s not that they necessarily directly react with each other, but that the absorption occurs with the same resources in the GI tract. So whether they’re physically separated or not, if they arrive together, they still compete. Hence the importance of staggering, or getting the right ratios if they arrive together.