Soylent and multivitamins


Soylent has vitamin E in the form of dl-alpha-tocopheryl-acetate which is a synthetic form and is associated with adverse effects. (1,2) Even “natural” isolated/purified alpha-tocopherol is associated with adverse effects.

I haven’t done a full discovery on folic acid, but an increased risk of stroke is also seen with alpha-tocopherol – again only associated with alpha-tocopherol taken in its isolated form. (1, 2) When alpha-tocopherol is taken with other mixed vitamers from the vitamin E family it is associated with a reduced risk of stroke. (3,4)

The key here is to avoid single vitamers, and opt for a broad-spectrum mixture of vitamers. There are about 13 different E vitamers that can be found in plant foods (e.g., tocopherols + tocotrienols).

  1. The effect of vitamin e and beta carotene on the incidence of lung cancer and other cancers in male smokers.
    1994. N. Engl. J. Med. 330(15):1029–35

    1. Schofield PM, et al. 1996. Randomised controlled trial of vitamin e in patients with coronary disease: cambridge heart antioxidant study
      Stephens NG, Parsons A,
      (chaos). Lancet. 347(9004):781–86
  2. Clinical investigation of the protective effects of palm vitamin E tocotrienols on brain white matter
    Gopalan Y, Shuaib IL, Magosso E, Ansari MA, Abu Bakar MR, Wong JWet al.
    Stroke, 2014

  3. Tocotrienol vitamin E protects against preclinical canine ischemic stroke by inducing arteriogenesis.
    Rink C., et al.
    J Cereb Blood Flow Metab. 2011 Nov;31(11):2218-30.